Comments on the National Toxicology Program Draft Background Document for Formaldehyde A Meta-Analysis of Formaldehyde Exposure and Risk of Leukemia and Nasopharyngeal Cancer
نویسنده
چکیده
In 2006, the International Agency for Research on Cancer (IARC) classified formaldehyde as carcinogenic to humans (IARC, 2006). In Monograph 88, IARC decided that the epidemiologic evidence available was strong but not sufficient to conclude that formaldehyde specifically causes leukemia in humans. However, IARC noted that studies reporting excess mortality from nasopharyngeal cancer (NPC) provided sufficient evidence of formaldehyde's carcinogenicity, thus providing the basis for the labeling of formaldehyde as carcinogenic. The NPC results were based primarily on the statistically significant excess of NPC deaths among industrial workers exposed to formaldehyde in a large US cohort.
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